CLAW FOR ARTHRITIS
Nancy Walsh. Internal Medicine News. June 2005
ORAL GLUCOSAMINE DELAYS KNEE REPLACEMENT SURGERY
Karel Pavelka, MD, reported at the Annual European Congress of Rheumatology, that the use of oral glucosamine by patients with osteoarthritis resulted in a marked reduction of knee replacement surgery for at least 5 years after the drug is stopped. He presented a 5-year follow-up on a double-blind placebo-controlled trial involving 202 patients randomized to glucosamine 1,500 mg once daily or placebo for 5 years.
The glucosamine group had beneficial, radiographically measurable changes in joint structure that persisted for years after the treatment. This is exciting news, on already accumulating data, for a disease-modifying drug in osteoarthritis.
Bruce Jancin. Denver Bureau. Internal Medicine News. Aug 2005
THERAPIES FOR OSTEOARTHRITIS
In the U.S., more is spent on alternative therapies for osteoarthritis than any other medical condition. Both glucosamine and chondroitin have been shown to have antiinflammatory pain-reducing benefits with fewer side effects compared to NSAIDS. SAMe, may be as effective as NSAIDS with less side effects, but is more expensive. Studies on DMSO have shown conflicting results. Ginger and cetyl myristoleate have no proven clinical usefulness for the treatment of osteoarthritis.
|ALTERNATIVE THERAPIES FOR
TRADITIONAL DISEASE STATES: OSTEOARTHRITIS
Vincent Morelli, MD; Christopher Naquin, MD; Victor Weaver, MD
Louisiana State University Health Sciences Center, Kenner, Louisiana
American Family Physician. January 15, 2003 / Volume 67, Number 2