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Family Cruciferae
Brokoli
Brassica oleracea
Broccoli


Scientific names Common names
Brassica oleracea Linn. Wild cabbage 
Brassica sykvestris (L.) Mill. Headless cabbage

Botany
A headless member of the cabbage family. The flowers are numerous in compact clusters. Flowers are harvested green and sold in the market as vegetable.

Distribution
Cultivated especially in the Baguio area.

Parts used
Flowers and leaves.

Chemical constituents and properties
• Considered anthelmintic, cardiotonic, diuretic, laxative and stomachic.
• Leaves are cardiotonic and stomachic.
• Phytochemicals: Glucosinolates, dithiolthiones, indoles, glucoraphanin, S-methyl cysteine sulfoxide, isothiocyanates, indole-3-carbinol.
• High in antioxidaqnt and anticancer compounds.

Uses
Nutrition
Good source of vitamin A, vitamin B complex, vitamin C and minerals.
Good for anemia because of abundant iron content.
Folkloric
- Externally used for gout and rheumatism.
- Decoction of flowers are carminative, emollient, diuretic.
- Poultice of leaves used for cleaning infected wounds – midrib removed, leaf ironed and placed on wound while hot.
- Used for gastrointestinal maladies.
- Both leaves and flowers are used for scurvy and xerophthalmia.


Studies
Antioxidative / Anti-Diabetic:
Study on the antioxidative effect and protective potention against diabetes in both in vitro and diabetic rat model showed an antioxidative effect and protection against diabetic-induced oxidative stress in an in-vivo model. (2) Study showed antioxidant and glucose lowering activitides in streptozotocin-induced diabetic rats.
Biologic Activities / Constituents:
(1) Studies show decreased mortality rates in radiation-exposed lab animals fed broccoli and cabbage (2) Some isothiocyanates have been shown to inhibit tumors induced by chemical carcinogens. (3) Rats fed with indole glucobrassicin showed lower incidence of chemically induced tumors (4) Studies also suggest compounds in broccoli can protect against macular degeneration. (5) Indole-3-carbinol showed preventive effects on endometrial carcinogenesis in mice. (6) Inhibitory effects of sulforaphane on H. pylori and prevents benzo-a-pyrene-induced stomach tumors. (8) Cancer cells with a lot of Bcl-2 has increased resistance to chemotherapy drugs. Study showed that Bcl-2 can not protect cancer cells against vegetable phytochemic isothiocyanates.
Anti-cancer:
Compounds found in cruciferous vegetables were found to block lung cancer progression in animal studies and tests on human lung cancer cells.
Antioxidant / COPD/ Smoking:
Study showed broccoli can boost antioxidants that counter chemical triggers to COPD and other negative effects of tobacco smoke.
Antioxidative:
Study on the antioxidative effect and protective potention against diabetes in both in vitro and diabetic rat model showed an antioxidative effect and protection against diabetic-induced oxidative stress in an in-vivo model.
Wound Healing: Administration of topical cabbage extract and egg while once a day in second degree burn wounds showed enhancement of healing. Results were comparable to silver suphadiazin group.
Hepatoprotective / Antioxidant: Study suggests broccoli possesses hepatoprotective activity probably through it antioxidative effects on hepatocytes due to its flavonoids and sulfurated compounds.
Diabetic Nephropathy Amelioration : Daily ingestion of RC polar extract ameliorates oxidative stress and ameliorates diabetic nephropathy.

Availability
Cultivated.


Additional Sources and Suggested Readings
(1)
Protective Effects of Broccoli (Brassica oleracea) against Oxidative Damage in Vitro and in Vivo / Cho Eun Ju et al / Journal of nutritional science and vitaminology 52(6) pp.437-444 20061200 / The Vitamin Society of Japan
(2)
The Effect of Compound of Brassica Oleracea L.and Egg-white on Burn Wound Healing in Rat / Dr Gholamreza Hasanzadeh and Naser Mehdikhanloo / Journal of Sabzevar School of Medical Sciences Volume11/ Number 4/ Winter 2004-2005
(3)
Antihyperglycaemic And Antioxidant Activity Of Brassica Oleracea In Streptozotocin Diabetic Rats / Vijaykumar P Rasal et al / The Internet Journal of Pharmacology™ ISSN: 1531-2976
(4)
Evaluation of Hepatoprotective Activity of Broccoli ‘Brassica oleracea’ in Rats / Tawfeq Al-Howiriny / Hungarian Medical Journal • Vol 2 No 1 • Mar 2008 / 10.1556/HMJ.2.2008.1.16

(5)
Broccoli can battle chronic obstructive pulmonary disease / Health and Fitness Archive Site
Northeast Ohio Health and Medical Consumer News
(6)
Brassica oleracea / Wild Cabbage / Plants For A Future
(7)
Cancer breakthrough: Medical nutrient in broccoli found to kill cancer cells / Natural News / September 18, 2006
(8)
Compounds in broccoli, cauliflower, and watercress block lung cancer progression / Medical News Today

(9)
Red Cabbage (Brassica oleracea) Ameliorates Diabetic Nephropathy in Rats / Hazem A H Kataya and AlaaEldin A Hamza / Oxford Journals Medicine Evidence-based Compl. and Alt. MedicineeCAM Advance Access10.1093/ecam/nem029


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