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Family Caesalpiniaceae
Orchid tree
Bauhinia variegata Linn.

POOR MAN'S ORCHID
Yang ti jia

Scientific names Common names
Bauhinia chinensis (DC.) Vogel Butterfly tree (Engl.)
Bauhinia decora Uribe Camel's foot (Engl.)
Bauhinia variegata Linn. Mountain ebony (Engl.)
Bauhinia variegata var. variegata Red flowered bauhinia (Engl.)
Phanera variegata (L.) Benth. Orchid tree (Engl.)
  Poor man's orchid (Engl.)
Orchid tree is an English common names shared by several Bauhinia species: (1) B. variegata (2) B. purpurea and (3) B. monandra.
Butterfly tree, derived from the "butterfly" shape of the leaves common to many Bauhinia species, is a common name shared by many Bauhinia species, among them: B. purpurea, B. monandra, B. variegata.
Bauhinia variegata L. is an accepted name The Plant List

Other vernacular names
ASSAMESE: Kotora, Kurol.
BENGALI: Kanchana, Raktakanchan.
BURMESE: Bwaycheng, Bwechin.
CHINESE: Yang ti jia.
FRENCH: Arbe de saint Thomas, Bauhinia panachee.
HINDI: Barial, Gurial, Kachnar, Kanchanar, Koliar, Padrian.
KANNADA: Arisinantige, Ayata, Bilikanjivala, Irkubalitu.
MANIPURI: Chingtrao.
MALAYALAM: Chuvanna mandharam, Kovidaram.
NEPALI: Koiralo.
PUNJABI: Kanchnar.
SANSKRIT: Ashmantaka, Asphota, Chamarika, Chamari, Kantar, Karaka, Suvarnara, Yugapatraka.
TELUGU: Bodanta, Mandara, Mandari.

Gen info
Bauhinia is a genus of more than 200 species. The genus was named after the Bauhin brothers, Swiss-French botanists. The leaves share the double-leaf configuration of a heart, or more popularly, that of a butterfly. (Also see: Alibangbang / Bauhinia malabarica)

The Hongkong orchid tree (Bauhinia blakeana is named after one of the British Governors of Hongkong, Sir Henry Blake, 1898-1903) and is now the floral emblem of Hongkong. The flower looks like an orchid, and thus has earned the name "Orchid Tree." It is usually sterile, and debated as of hybrid origin between Bauhinia variegata and Bauhinia purpurea.

Botany
Bauhinia variegata is a moderate sized deciduous tree growing to a height of 10 meters or more. Leaves are alternate and lobed to one-third of their length, heart-shaped at the base with a deep cleft that divides the apex. Flowers are in short racemes, faintly fragrant, petals broad and overlapping, lavender to purple or white. Pods are long, narrow, flattened,10 to 15 centimeters by 1.5 to 2.5 centimeters, containing 5 to 10 seeds.

Distribution
Ornamental cultivation.

Constituents
- Yields flavonoids:quercetin, rutin, apigenin and apigenin 7-O-glucoside.
- Phytoscreening reported flavonoids, lectin and albumin.
- Stem yields sitosterol, lupeol, kaempferol-3-glucoside and 5,7-dihydroxy and 5,7-dimethoxy flavanone-4-O--L-rhamnopyranosyl--Dglucopyranosides.
- Flowers contain cyanidine-3-glucoside, malvidin-3-glucoside, malvidin-3-diglucoside, and peonidin
3-diglucoside, kaempferol-3-galactoside and kaempferol-3- rhamnoglucoside.

- Root bark yielded a new flavanone: (2S)–5,7-dimethoxy-3'- 4' -methylene dioxyflavanone and a new dihydrobenzoxepin 5,6-dihydro-1,7dihydroxy-3,4- 2,3 dimethoxy-2-methyldibenz (b,f) oxepin.
- Phytochemical screening of leaf and bark yielded carbohydrates, resin, saponin, terpenoids, alkaloids, steroids, flavanoids, tannins, and proteins. (40)
- Fractionation of crude petroleum ether extract of stem bark isolated heptatricontan-12, 13-diol, friedelin, n-docosanoic acid, stigmasterol, β-sitosteryl, n-hexadecanoic acid, lupeol. A methanolic extract yielded eriodictyol and quercetin. (42)
- Phytochemical screening of bark extracts yielded steroid, phenol/tannin, glycoside/sugar, carbohydrate and terpenoids. (see study below) (46)
- Bark extract showed high phenolic content (156.30 ± 0.3 mg GAE/gm) and flavonoid content )14.04 ± 1.4 mg QE/gm). (see study below) (53)
- Study of methanol extract of bark isolated kaempferol, stigmasterol, protocatechuic acid-methyl ester (PCA-ME) and protocatechuic acid  (PCA).  (see study below)  (54)
- Qualitative study for chemical constituents of young premature flower buds  yielded  alkaloids, reducing sugars, terpenoids, glycosides, tannins, flavonoids and carbohydrates. Saponins were not present in any of the solvent extracts. Anthraquinones were present in some flower bud samples.   (55)
-   Study of stems isolated a new phenanthraquinone bauhinione elucidated as 2,7-dimethoxy-3-mrthyl-9,10-dihydrophenanthrene-1,4-dione. (60)

Properties
- Antinociceptive, anti-inflammatory, antipyretic, anthelmintic.
- Bark is alterative, astringent and tonic.

- Studies have suggest antioxidant, anti-inflammatory, antimicrobial, anticancer, nephroprotective, hepatoprotective, anti-obesity, antihyperlipidemic, antidiabetic, anthelmintic, immunomodulatory, antipyretic, antimutagenic, nootropic, phytotoxic properties.

Parts used
Bark, leaves, flowers, roots.

Uses
Edibility
- In India, flower buds used as a vegetable dish.
Folkloric
- In the Philippines. infusion of new flowers used for dysentery.
- Elsewhere the bark is used for the treatment of skin diseases, scrofula and ulcers.
- Bark used to treat and diarrhea.
- The dried buds are used in the treatment of piles, dysentery, diarrhea and worms.
- Root is used as an antidote to snake poison.
- Decoction of the root used for dyspepsia.
- In India, powdered bark used as tonic, for strains, ulcers, skin disease. Also, extracts of bark used for treatment of cancer. Roots used for dyspepsia and as antidote for snake bites.
- In India, Mundas women use flower decoction as galactagogue. Dried flower buds in water used as vermifuge. Santals women use dried flower buds with paste of black pepper to regular vaginal discharge. Andh and Bhil use the leaves as laxative. (37)
- In Konkan, fresh bark juice used as expectorant. Bark used with dried ginger as internal remedy for scrofula. South Indians used leaf decoction to relieve headaches in malarial fever. (37)
- In Ayurveda, plant pacifies vitiated kapha. Used to treat diarrhea, goiter, jaundice, rectal prolapse, diabetes, inflammation, worms, tumors, piles, menorrhagia, hemoptysis, and cervical lymphadenopathy.
- Roots used as antidote to snake poison.
Others
- Dye: Bark reported to be used in dyeing, yielded various fast shades of brown color. (37)


Studies

Antibacterial: Evaluation of antibacterial activity and phytochemical analysis of Bauhinia variegata L. bark: Defatted acetone and methanol extracts showed the most antibacterial activity. (1) The aqueous and methanol extracts of 12 plants from different families was studied for antibacterial activity against B cereus, S epidermis, E aerogenes, P vulgari and S typhimurium. Among the plant screened, B variegata bark showed the best antibacterial activity. (12)
Anti-Inflammatory: Study isolated six flavonoids and one triterpene caffeate. The seven compound significantly and dose-dependently inhibited function involved in the inflammatory processes. Results support the folkloric use of BV in its use for inflammatory conditions.
Anti-Inflammatory / Flavonol Glycoside:
Study yielded a novel flavonol glycoside 5,7,3',4'-tetrahydroxy-3-methoxy-7-O-alpha-L-rhamnopyranosyl(1-->3)-)-beta-galactopyranoside from the root which showed anti-inflammatory activity. (6)
Hepatoprotective: Hepatoprotective Properties of Bauhinia variegata Bark Extract: In carbon tetrachloride intoxicated rats, extract of stem bark of Bv showed significant hepatoprotective activity and a promising agent for that purpose. (7)
Chemopreventive / Cytotoxic: Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine (DEN) induced liver tumors and human cancer cell lines: Results showed chemopreventive and cytotoxic effect of ethanol extract of BV against induced DEN liver tumor and human cancer lines. (14)
Antitumor / Cytotoxic: Ethanol extract of B variegata evaluated against Dalton's ascitic lymphoma in Swiss albino mice showed significant enhancement of survival time and reverse hematologic parameters consequent to tumor inoculation. (5)
Antioxidant / Antihyperlipidemic: Study of alcoholic and aqueous extract of Bv effectively decreased plasma cholesterol, triglycerides, LDL, VLDL and increase HDL levels and also showed significant antioxidant activity. EBV was found to be a potent cytotoxic toward EAC tumor cell.
(9)
Pharmacognosy / Phytochemicals: Study yielded steroid, saponin, flavonoids, alkaloids and tannins.
Immunomodulatory: Study on the ethanolic extract of the stem bark of Bv showed significant increase in the primary and secondary humoral antibody response and show promise as an immunomodulatory agent, probably through stimulation of both the specific and nonspecific arms of immunity.
Immunomodulatory: Study evaluating the immunomodulatory activity of stem bark extracts
showed predominantly significant activity on in vitro human neutrophils in all parameters. Results suggested a possible immunostimulating effect. (10)
Anti-Diabetic: Study showed the presence of insulin-like properties in the leave of Bv. The activity of this insulin-like protein on serum glucose levels in diabetic mice was similar to that of commercial swine insulin used a control. (11)
Anthelmintic: Study showed significant anthelmintic activity by methanolic extract of B variegata against both mature male and female Haemonchus contortus. (13)
Hypolipidemic: Study of extracts of bark of Bauhinia variegata showed significant reduction in total cholesterol and LDL in Triton-induced hyperlipidemia in rats. The HDL increase was not significant. (15)
Anti-Obesity Effect / Hypolipidemic / Root / Stem and Root Bark: Study of root extract showed an anti-obesity activity attributed to its hypophagic, hypoglycemic and hypolipidemic effect. (16) Study evaluated the antiobesity effect of methanolic stem and root barks of B. variegata in female rats fed with hypercaloric diet. Results showed increased brain serotonin level and HDL with decrease in TC, triglycerides and LDL. The antiobesity effect may be attributed to the presence of ß-sitosterol in the stems and the tendency of the extract to reduce lipid profile and affect brain serotonin level. (49)
Nephroprotective / Gentamicin Toxicity / Antioxidant / Roots: Study of ethanol and aqueous roots extracts in gentamicin-induced nephrotoxicity in rats showed significant nephroprotective activity. Antioxidant activity was shown on a DPPH assay model. (17)
Chemopreventive / Bark: Study of B. variegata bark in mice showed a chemopreventive potential against DMBA-induced skin carcinogenesis. (18)
Antimutagenic / Bark: Study of bark extract B. variegata showed a preventive potential against cyclophosphamide-induced micronucleus formation in Swiss mouse bone marrow cells.
Antipyretic: Study of ethanolic extract showed antipyretic activity probably through inhibition of prostaglandin synthesis in the hypothalamus. (19)
Anti-Eosinophilic: Study of aqueous and ethanol extracts of BV against milk-induced leucocytosis and eosinophilia in mice showed a significant dose-dependent reduction in total leukocyte and eosinophil counts suggesting an antieosinophilic activity. (20)
Anti-Ulcer / Analgesic: Study of root extracts showed significant dose-dependent analgesic and significant anti-ulcer activity. The activities were attributed to the presence of flavonoids. (21)
Chemopreventive / Cytotoxic: Study of ethanol extract of BV showed significant chemopreventive and cytotoxic effect against DEN (N-nitrosodiethylamine)-induced liver tumor and human cancer cell lines.  (22)
Antioxidant / Free Radical Scavenging / Leaves / Bark: Study showed the extract of leaves of G. pentaphylla and Bauhinia variegata inhibited free radical scavenging activity. The effect was attributed to flavonoids, phenolics and other phytochemical constituents. (24) Study evaluated aqueous and ethanolic bark extracts for in vitro free radical scavenging activity by DPPH, NO, OH radical and reducing power assays. The ethanolic extract showed significant NO scavenging activity while the aqueous extract showed great potential against ROS (reactive oxygen species) and RNS (reactive nitrogen species). Results suggest a source of natural antioxidants which protect against oxidative stress. (46)
Antipyretic: Study of ethanolic extracts of B. variegata and G. pentaphylla exhibited significant antipyretic activities in Brewer's yeast induced pyrexia in rats. Activity was attributed to inhibition of prostaglandin synthesis in the hypothalamus. (25)
Chemopreventive / DBMA-induced Skin Carcinogenesis: Study investigated the anticarcinogenic activity of B. variegata bark extract in a skin papilloma model in Swiss albino mice. Results showed a chemopreventive role for bark extracts against DBMA-induced skin carcinogenesis in mice with decrease in rate of tumor incidence, number of papillomas, tumor yield and tumor burden. (26)
Anti-Inflammatory: Study investigated the anti-inflammatory potential of leaves, barks, and roots using three in vivo animal models: carrageenan induced rat paw edema, cotton pellets induced granuloma formation, and adjuvant induced arthritis in rat. An ethanol extract and petroleum ether extract demonstrated anti-inflammatory activity in the three bioassays. (27)
Analgesic / Antifungal / Cytotoxic: Study investigating an ethanolic extract of the plant showed analgesic activity by eddy's hot plate method, in vitro cytotoxicity against DLA cells lines by Trypan blue assay method, and good antifungal activity against Aspergillus fumigatus and Candida albicans. (28)
Radical Scavenging / Natural Antioxidant: Study of leaf, stem bark, floral buds extracts showed remarkable concentration dependent free radical scavenging and reducing power. Results suggest a potential source of natural antioxidant. (29)
Antibacterial / Anticancer / Antioxidant / Leaves: Study evaluated the phytochemical, antimicrobial, and anticancer activities of B. variegata leaf extracts. Petroleum ether and chloroform fractions showed considerable inhibition against Klebsiella pneumonia. An ethanol extract showed the lowest MBC (3.5 mg/mL) against Pseudomonas spp. Dose dependent response was observed in reducing power of the extracts. Many extracts showed significant antioxidant response in beta carotene bleaching assay. Aqueous fraction showed pronounced cytotoxic effect against against DU-145, HOP-62, IGR-OV-1, MCF-7, and THP-1 human cancer cell lines with 90–99% cell growth inhibitory activity. (32)
Nephroprotective / Leaves: Study of methanolic extract of leaves showed nephroprotective activity in gentamicin induced nephrotoxicity. The extract showed a very good protective effect (p<0.001) in the control of creatinine, urea, and uric acid. (33)
Cytotoxic Activity / HeLa Cell Line: Study investigated the in vitro anticancer activity of a flavonoid rich fraction of an ethanolic bark extract on HeLa cell lines. Results confirm the induction of apoptosis by in malignant HeLa cell lines at a dose level of 191.5 µg/ml and also arrested the replication of cells at G0/G1 phase. (34)
Acute and Repeated Dose Toxicity / Leaves / Stem Bark: Study investigated the safety of a methanolic extract of leaves after acute and repeated dose administration in rodents. NOAEL (no-observed adverse effect level) of the ME was found to be 2000 mg/kg. In repeated dose toxicity study, no mortality was seen during a 28-day period. Histopathology of important organs showed normal structure. Results showed the leaves to be safe in acute and repeated dose toxicity studies in mice and rats. (35) Study evaluated the toxicity of aqueous extract of stem bark of Bauhinia variegata in Sprague-Dawley rats. Results showed maximally tolerated dose (MTD) of 5,000 mg/kg in acute toxicity study and lowest observed adverse effect level of 1,000 mg/kg in repeated-dose toxicity study. (50)
Anti-Inflammatory / Leaves: Study evaluated the anti-inflammatory activity of a leaf extract using three in vivo animal models: carrageenan induced rat paw edema, cotton pellets induced granuloma formation, and adjuvant induced arthritis in rats. Both ethanol extract and PE fraction demonstrated activity in all three bioassays. The activity compared favorable with diclofenac. (36)
• Antimicrobial / Leaves: Study of an ethanol extract of leaves of B. variegata showed varying degrees of inhibitory activity against all tested bacteria and fungi. The extract showed maximum activity against Salmonella typhi (27mm) followed by Vibrio cholera, K. pneumonia, E. coli and S. aureus. Extract was very effective against dermatophyte, T. mentagrophytes and plant pathogen, Mucor hiemalis. (38)
• Antitumor Potential / Melanoma Tumor: Study evaluated hydromethanolic extracts of leaf, stem bark, and flower of B. variegata for antitumor activity against melanoma tumor (B16F10) in C57BL mice. Results showed significant effect evidenced by a dose dependent response in tumor volume, inhibition rate, life span time and antioxidant parameters. The extracts showed to be relatively safe from toxic effects. (39)
• Nootropic: Study evaluated the nootropic potential of B. variegata in rats using elevated plus maze, rotating rod apparatus, baclofen-induced catatonia, and diazepam-induced amnesia testing. Overall, the flavonoid-rich fraction was found to enhance the performance of murine models. Study concludes that B. variegata possess nootropic potential which can be attributed to the presence of flavonoids. (41)
• Mast Cell Stabilizing / Potential for Asthma Treatment / Stem Bark: Study evaluated stem bark extracts of B. variegata for mast cell stabilizing activity and the basis of its used in the treatment of asthma and other respiratory conditions in Ayurvedic medicine. Results showed significant protection of mouse mast cell from degranulation (71.18%) and reduced mortality (50%) in mice treated with toxicant (compound 48/90). Results showed potent mast cell stabilizing activity suggesting potential for use in the treatment of asthma. (43)
• Antimicrobial / Antioxidant / Phytotoxic / Immunomodulatory: In antimicrobial assay, the plant showed highest zones of inhibition against B. cereus (12mm) and Rhizopus (11mm). In antioxidant assay, it showed highest radical scavenging at 43.48% compared to ascorbic acid at 89.25%. Immunomodulatory assay at highest concentration of 250 µg/mL showed 75.1% effect suggest potential anti-inflammatory activity. In phytotoxicity assay, B. variegata showed 20% activity. (44)
• Antiviral / Treatment of Coxsackievirus B3 Infection / Leaves: Coxsackievirus B3 is a common viral myocarditis in humans, especially infants and young children. Study evaluated the antiviral activities of B. variegata extracts against CVB3 infection in vitro and in vivo. A methanol extract of leaves showed highest in vitro antiviral effect probably by blocking viral receptors. The extract reduced morbidity and mortality, viral titers, and histopath changes in heart tissue of infected mice, while maintaining AST, CK, and LDL enzymes at normal levels. Results suggest a potential role in the treatment of CVB3 infection. (45)
• Silver Nanoparticles / Antibacterial / Bark: Study reports on the green eco-friendly, cost-effective biogenic synthesis of silver nanoparticles using B. variegata bark extract as reducing, stabilizing, and capping agent. The synthesized silver nanopartilces exhibited very effective antibacterial activity against pathogenic bacteria i.e., B. subtilis, E. coli, P. aeruginosa and S. aureus. (47)
Antimicrobial / Anticancer Activities: Study evaluated extracts of B. variegata generated through in vivo and in vitro processes for antibacterial and anticancer activities. Activity was greater against gram positive bacteria compared to gram negative bacterial. In vitro cytotoxicity screening showed same degree of inhibition of EAC mouse cell lines from both in vivo and in vitro sources. (48)
• Biodiesel Potential: Study reports on the use of B. variegata oil as source of biodiesel synthesis. 5.1%.At optimum conditions, the Bauhinia variegata methyl ester (BVME/biodiesel) yield was 9Engine performance and combustion curves of biodiesel blends were similar to diesel. (49)
• Molluscicidal / Leaves: Study of B. variegata leaf and Mimusops elengi bark showed molluscicidal activity against vector snail Lymnacea acuminata. Toxicity was time and concentration dependent. Ethanol extracts showed more toxicity than other extracts. The 24h LC50 of B. variegata was 20.3 mg/L. (51)
• Chronic Toxicity Study / Stem Bark Powder: Study evaluated the toxicity of stem bark powder suspension in TED (Therapeutic Equivalent Dose) of 350 mg/kg/day and five fold TED (1800 mg/kg/day) for 60 days in albino rats. Results of toxicity profile showed B. variegata bark is likely to produce toxic effect when administered in a five-times dose in powder form. (52) (see toxicity study 35 and 50 above)
• Antioxidant / Phytotoxic / Antimicrobial / Bark: Study evaluated a methanolic extract of B. variegata bark for antioxidant, antimicrobial, and phytotoxic activity. Results showed potent antimicrobial activity against S. aureus, S. typhi, B. subtilis and E. coli with zone of inhibition of 14, 12, 12, and 11mm, respectively. DPPH radical scavenging assay showed an IC50 f 6.48±0.08 µg/mL compared to IC50 of standard ascorbic acid of 45.93 µg/mL. Extract showed moderate phytotoxic activity of 65, 40, and 25% growth regulation with number of fronds 07, 12, and 15, respectively, comparable with standard drug paraquat. (see constituents above)  (53)
Antioxidant / Cytotoxic / Bark: Study of methanol extract of bark isolated kaempferol, stigmasterol, protocatechuic acid-methyl ester (PCA-ME) and protocatechuic acid  (PCA). The compounds were found to have significant antioxidant activity by ABTS and DPPH assays and cytotoxic activity using MTT dye reduction assay against  C-6 glioma rat brain, MCF-7 breast cancer and  HCT-14 colon cancer cell lines.  Results of study may be helpful for chemotaxonomic determinations and understanding the medicinal properties of B. variegata bark. (54)
Rhamnocitrin / Anticataract / Stem Bark: Approximately 25% of the populstion over 65 and about 50% over age 80 have vision loss because of cataract.  Oxidative damage to the lens is recognized as the initiating even in the pathogenesis of cataracts.  Rhamnocitrin, a flavonoid, possess strong antioxidant effects. Study evaluated the anticataract activity of rhamnocitrin isolated from B. variegata stem bark in bovine and chick embryo lens model. Results showed significant protection against cloudiness in lenses induced by hydrogen peroxide and hydrocortisone in a dose dependent manner. The anticataract activity of rhamnocitrin was attributed to its antioxidant property. (56)
Rhamnocitrin / Alzheimer's Disease / Bark: Acetylcholinesterase (AChE) and butyrylcolinesterase (BChE) act as promising protein targets for drug inhibitors to be designed to treat Alzheimer's disease. The in silico study evaluated the binding patterns of flavonids and alkaloids against AChE and BChE using molecular docking and molecular dynamics simulations approach. Molecular docking result showed that  dihydroquercetin binds with the active region of AChE and BChE, The in silico study predicts that Dihydroquercetin nay act as a good inhibitor for treating Alzheimer's disease. (57)
Galactose Specific Lectin / Antimicrobial / Seeds: A galactose-specific lectin was purified from seeds of B. variegata. The antimicrobial activity of the purified lectin was carried out by agar disc diffusion method. The lectin, named BVL, demonstrated remarkable antibacterial activity against pathogenic bacteria Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, and  Bacillus subtilis and showed significant antifungal activity against  Aspergillus niger and Penicillium crysogenum. (58)
Antiurolithiatic / Leaves: Study evaluated the in vitro antiurolithiatic activity of leaf aqueous and ethanolic extracts of B. variegata. Preliminary phytochemical screening yielded the presence of saponin glycosides, tropane alkaloids and acidic compounds. Results showed inhibition of growth of crystals increased with increase in extract concentration. (59)

Availability
Ornamental cultivation.

Updated  February 2022 / June 2018 / April 2016

PHOTOS / ILLUSTRATIONS
Photos © Godofredo Stuart / StuartXchange
OTHER IMAGE SOURCE: Flower Close-up/ Funchal - Bauhinia variegata (Orchideenbaum) IMG 2104.JPG / Hedwig Stoch / 23 thang 3 2008 / GNU Free Documentaion License/ Creative Commons / Wikipedia
SOURCES

Additional Sources and Suggested Readings
(1)
Evaluation of antibacterial activity and phytochemical analysis of Bauhinia variegata L. bark
(2)
Antinociceptive, Anti-Inflammatory and Antipyretic Properties of the Aqueous Extract
of Bauhinia purpurea Leaves in Experimental Animals

(3)
Antiinflammatory Activities of Flavonoids and a Triterpene Caffeate Isolated from Bauhinia variegata / Yerra Kotsewara Rao et al / Phytotherapy Research • Volume 22 Issue 7, Pages 957 - 962 / DOI 10.1002/ptr.2448
(4)
Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine
induced liver tumors and human cancer cell lines
/ B Rajkapoor et al / Journal of Ethnopharmacology
Volume 104, Issue 3, 6 April 2006, Pages 407-409 / doi:10.1016/j.jep.2005.08.074
(5)
Antitumour activity of Bauhinia variegata on Dalton’s ascitic lymphoma / B Rajkapoor
et al / Journal of Ethnopharmacology • Volume 89, Issue 1, November 2003, Pages 107-109 / doi:10.1016/S0378-8741(03)00264-2
(6)
Anti-inflammatory activity of a novel flavonol glycoside from the Bauhinia variegata Linn./ Yadava R N and Reddy V M / Nat Prod Res. 2003 Jun;17(3):165-9 /
(7)
In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn / G P Rajani and Purnima Ashok / Indian J Pharmacol • 2009 ;41:227-32
(8)
Pharmacognostical and Phytochemical Screening of Bauhinia variegata Linn leaves / Rajeh Gupta et al / Journal of Pharmacy Research 2009, 2(7),1196-1198
(9)
Hepatoprotective Properties of Bauhinia variegata Bark Extract / Surendra Bodakhe and Alpana Ram / YAKUGAKU ZASSHI • Vol. 127 (2007) , No. 9 1503-1507
(10)
Evaluation of the immunomodulatory activity of ethanolic extract of the stem bark of Bauhinia variegata Linn / M M Ghaisas et al / Int J Green Pharm 2009;3:70-4
(11)
Isolation and intracellular localization of insulin-like proteins from leaves of Bauhinia variegata / Azevedo C R et al / Brazilian journal of medical and biological research • 2006, vol. 39, no11, pp. 1435-1444/
(12)
Antibacterial and phytochemical studies on twelve species of Indian medicinal plants / Jigna Parekh and Sumitra Chanda / African Journal of Biomedical Research • Vol 10: 175-181, 2007
(13)
Anthelmintic activity of leaves of Bauhinia variegata
/ Anita Singh et al / Indian Veterinary Journal /

(14)
Bauhinia variegata / Ayurvedic Medicinal Plants
(15)
PROTECTIVE EFFECT OF BAUHINIA VARIEGATA EXTRACTS ON TRITON INDUCED HYPERLIPIDEMIA IN RATS / Biradar SS and Patil PA / Journal of Cell and Tissue Research Vol. 11(2) 2785-2788 (2011)
(16)
EVALUATION OF ETHANOLIC EXTRACT OF BAUHINIA VARIEGATA LINN. IN HIGH FAT DIET INDUCED OBESITY IN RATS /
*Yash Prashar, S. Venkataraman / International Journal of Phytopharmacology, 1(2), 2010, 103-108.
(17)
Effect of Ethanolic and Aqueous Extracts of Bauhinia Variegata Linn. on Gentamicin-Induced Nephrotoxicity in Rats / Rajesh Kumar Sharma*, Rajani G.P., Vivek Sharma, Komala N / Ind J Pharm Edu Res, Apr-Jun, 2011/ Vol 45/ Issue 2
(18)
Chemopreventive potential of Bauhinia variegata against DMBA-induced skin papillomagenesis in Swiss albino mice / Manju Singh and Raosaheb K. Kale / Cancer Prevention Research: January 2010; Volume 3, No 1, Suppl 1 / doi: 10.1158/1940-6207.PREV-09-A64
(19)
A Comparative Antipyretic Activity of the Crude Extracts of the Ariel Parts of Glycosmis pentaphylla and Bauhinia variegata / Mandal S, Upadhyay N, Sharma I, Rohit S, Mandloi A / Recent Research in Science and Technology 2011, 3(7): 16-18
(20)
Evaluation of effects of Bauhinia variegata stem bark extracts against milk-induced eosinophilia in mice / Ravindra G Mali, Avinash S Dhake / J Adv Pharm Tech Res, 2011;2:132-4 / DOI: 10.4103/2231-4040.82949
(21)
Analgesic and Anti-Ulcer Activities of Ethanol and Aqueous Extracts of Roots of Bauhinia variegata Linn. / Yanni R Kumar and G P Rajani / Intern Journ of Pharmacology 7(5):616-622, 2011
(22)
Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine induced liver tumors and human cancer cell line / B. Rajkapoor, B. Jayakar, N. Murugesh and D. Sakthisekaran / Journal of Ethnopharmacology, Volume 104, Issue 3, 6 April 2006, Pages 407-409 / doi:10.1016/j.jep.2005.08.074
(23)
In-vitro Immunomodulatory Activity of extracts of Bauhinia vareigata Linn Stem Bark on Human Neutrophils / J K Patil, S S Jalalpure, S Hamid, R A Ahirrao / IJPT, July 2010, Vol 9, No 2, 41-46
(24)
In-vitro Comparative Antioxidant Activity of Ethanolic Extracts of Glycosmis pentaphylla and Bauhinia variegata / Bhatia L, Bishnoi H, Chauhan P, Kinja K, Shailesh S / Recent Research in Science and Technology 2011, 3(7): 01-03
(25)
A Comparative Antipyretic Activity of the Crude Extracts of the Ariel Parts of Glycosmis pentaphylla and Bauhinia variegata / Mandal S, Upadhyay N, Sharma I, Rohit S, Mandloi A / Recent Research in Science and Technology 2011, 3(7): 16-18

(26)
Effect of Bauhinia Variegate Bark Extract on DMBA-Induced Mouse Skin Carcinogenesis: A Preliminary Study / Sonam Pandey and R.C. Agrawal / Global Journal of Pharmacology, 3 (3): 158-162, 2009 ISSN 1992-0075 © IDOSI Publications, 2009
(27)
In Vivo Study for Anti-inflammatory Activity of Bauhinia variegata L. Leaves / Santanu Saha, Subrahmanyam, K.S. Chandrashekar and Shashidhara C. Shastry / Pharmaceutical Crops, 2011, 2, 70-73
(28)
Analgesic, Antifungal and In-Vitro Cell Cytotoxic Studies of Bauhinia Variegata Bark Extract
/ Shyamkumar B*, Ishwar Bhat K / AJPTR, American Journal of PharmTech Research
(29)
In-Vitro Antioxidant and Free Radical Scavenging Activity of Bauhinia Variegata Linn / Sonam Pandey*, R. C. Agrawal* and S. Maheshwar / International Journal of Scientific and Research Publications, Volume 2, Issue 2, February 2012 1
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Bauhinia variegata / Synonyms / The Plant List
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Kachnar / Common names / Flowers of India
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Bauhinia variegata Leaf Extracts Exhibit Considerable Antibacterial, Antioxidant, and Anticancer Activities / Amita Mishra, Amit Kumar Sharma, Shashank Kumar, Ajit K. Saxena, and Abhay K. Pandey / BioMed Research International, Volume 2013 (2013) / http://dx.doi.org/10.1155/2013/915436
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Evaluation of Nephroprotective Activity of the Methanolic Extract of Leaves of Bauhinia variegata Linn, (Family-Caesalpiniaceae) / Prusty KB*, Harish B, Mamatha CH / Journal of PharmaSciTech 2012; 2(1):16-19
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APOPTOSIS AND FLOWCYTOMETRIC STUDIES OF BAUHINIA VARIEGATA BARK EXTRACT / SHYAM KUMAR B*, K. ISHWAR BHAT / Asian Journal of Pharmaceutical and Clinical Research, Vol 7, Suppl 1, 2014
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Acute and Repeated Dose Toxicity Studies of Methanol Extract of Bauhinia variegata Leaves / Yogesh Anant Kulkarni and Sona Warrier / The FASEB Journal, Vol 26, No1, Supplement 1124.5
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In Vivo Study for Anti-inflammatory Activity of Bauhinia variegata L. Leaves / Santanu Saha, E. V.S. Subrahmanyam, K. S. Chandrashekar, Shashidhara C. Shastry / Pharmaceutical Crops, 2011, 2: 70-73
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TRIBAL USES OF MEDICINAL PLANTS OF RAJASHTHAN:KACHNAR. / SANTOSH SHARMA AND *ASHWANI KUMAR / International Journal of Life Science & Pharma Research, Oct-Dec 2012; Vol 2, Issue 4
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Antimicrobial Activity Of Medicinal Plant Bauhinia variegata Linn. / Gayathri Gunalan, A.Saraswathy* and Vijayalakshmi Krishnamurthy / International Journal of Pharmacy and Biological Sciences, Oct-Dec 2011; Vol 1, Issue 4: pp 400-408
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In vivo antitumor potential of extracts from different parts of Bauhinia variegata linn. Against b16f10 melanoma tumour model in c57bl/6 mice / Sonam Pandey / Applied Cancer Research (2017) 37:33 / DOI 10.1186/s41241-017-0039-3
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Physicochemical and Phytochemical Analysis of Bauhinia variegata Modern analytical HPTLC Fingerprinting. / Kalpana Pachouri, Sandeep Yadav / International Journal of Scientific & Engineering Research, Volume 6, Issue 8, August-2015
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Nootropic potential of Bauhinia variegata: A systematic study on murine model / Nishikant Jatay, Aditya Ganeshpurkar, Nidhi Gupta, Chitrangda Ayachi, Ruchi Ramhariya, Divya Bansal, Nazneen Dubey / Archives of Medicine & Health Sciences (2014); Vol 2, Issue 1: pp 29-35
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ISOLATION OF PHYTOCONSTITUENTS FROM THE STEM BARK OF BAUHINIA VARIEGATA LINN. / Vijay Kumar MMJ*, Eswarappa B, Yadav D. Bodke, Jayadevaiah KV, Basavaraja HS / PharmaTutor, 2014; Vol 2, Issue 9: pp 150-156
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Mast Cell Stabilizing Activity of Bauhinia variegata / Ravindra G Mali & Avinash S Dhake / Journal of Herbs, Spices & Medicinal Plants, 2011; Vol 17, Issue 3 / https://doi.org/10.1080/10496475.2011.602204
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Study of Phytochemical, Anti-Microbial, Anti-Oxidant, Phytotoxic, and Immunomodulatory Activity Properties of Bauhinia variegata / Jaya Bhandari, Pratiksha Thapa, Prasodhan Niraula, Nita Thapa, Nikita Shrestha, Bhupal Govinda Shrestha / Journal of Tropical Life Science (2017); Vol 7, No 1
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In Vitro and In Vivo Evaluation of Bauhinia variegata Extracts to Prevent Coxsackievirus B3 Infection 
/ Mohamed Shaheen, Maria Borsanyiova, Sami Mostafa, Shubhada Bopegamage and Nagwa El-Esnawy / J Proteomics Bioinform 10:73-78. / doi: 10.4172/jpb.1000426
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Free radical scavenging activity of bark extracts of Bauhinia variegata L. / Bhagya Bhaskar / Asian Journal of Biomedical and Pharmaceutical Sciences; 3(22) 2013, 9-13.
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Biogenic Synthesis of Silver Nanoparticles using Bauhinia Variegata Bark Extract and its Antibacterial Efficacy / Hiral Vaghela, Rahul Shah and Kokila Parmar* / Int. J. Nano. Chem. 3, No. 2, 45-49 (2017)
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Evaluation of Antimicrobial and Anticancer activities of Methanol Extract of in vivo and in vitro grown Bauhinia variegata L. / Sinha Kanak and Verma Anita K.* / International Research Journal of Biological Sciences, Oct 2012; Vol. 1(6), pp 26-30
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Anti effect of Bauhinia variegata bark extract on female rats fed on hypercaloric diet
/ Gunasekaran Balamurugan, Palayan Muralidharan / Bnagladesh Journal of Pharmacology, Vol 5, No 1 (2010)
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Acute and 28-Day Repeated Dose Oral Toxicity of Bauhinia variegata (Caesalpiniaceae) Stem Bark Extract / Vikash S Makadiya, Yogesh A Kulkami & Kishori G Apte / Journal of Herbs, Spices & Medicinal Plants (2015); Vol 21, Issue 2
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Characterization of the molluscicidal activity of Bauhinia variegata and Mimusops elengi plant extracts against the fasciola vector lymnaea acuminata / Kanchan Lata Singh; D.K. Singh; Vinay Kumar Singh / Rev. Inst. Med. trop. S. Paulo vol.54 no.3 São Paulo, May-June 2012
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Chronic toxicity study of stem bark powder of Kanchanara (Bauhinia variegata L.) in albino rats / Kolhe R, Acharya RN, Ashok BK, Ravishankar B / Indian Journal of Natural Products and Resources (2014); 5(3)
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Antioxidant, Phytotoxic and Antimicrobial Activities of Methanolic Extract of Bauhinia variegata Barks / Khaga Raj Sharma, Surya Kant Kalauni and Suresh Awale / Journal of Institute of Science and Technology, 2015, 20(2):  pp 37-41
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Isolaation of Phytochemicals from Bauhinia variegata L. Bark and Their In Vitro Antioxidant and Cytotoxic Potential / Neha Sharma, Anket Sharma,  Renu Bhardwaj et al / Antioxidants,  2019; 8(10)  /
DOI: https://doi.org/10.3390/antiox8100492
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Qualitative Study on the Phytochemical Constituents of the Flower Buds of Bauhinia variegata / Kew KS, Naeem Hassan KHan et al / Madridge J Pharm Res., 2018;p 2(1): pp 47-51 /
DOI: 10.18689/mjpr-1000108
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Anticataract activity of rhamnocitrin isolated from Bauhinia variegata stem bark / Surendra H Bodakhe, Alpana Ram. Devi Prasad Pandey / Oriental Pharmacy and Experimental Medicine, 2012; 12: pp 227-232 / DOI: https://doi.org/10.1007/s13596-012-0059-1
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Screening and identification of secondary metabolites in the bark of Bauhinia variegata to treat Alzheimer's disease by using molecular docking and molecular dynamics simulations / Noopur Khare,   Sanjiv Kumar Maheshwari, Abhimanyu Kumar Jha / Journal of Biomolecular Structure and Dynamics,  2021; 39(16)L pp 5988-5998 / DOI: https://doi.org/10.1080/07391102.2020.1796798
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Isolation and purification of a galactose specific lectin from seeds of Bauhia variegata and evaluation of its antimicrobial potential / Ravi Prakash Miishra, Aijaz  Ahmad Ganaie,  Aashiq Hussain Allaie /  International Journal of Pharmaceutical Science and Research,  20`6; 7(2): pp 804-809 /  eISSN: 0975-8232  / pISSN:  2320-5148:
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Phytochemical and in vitro antiurolithistic studies on the leaf extracts of Bauhinia variehsts Linn / Vani Mamillapalli,  Vanni Katha et al / International Journal of Pharmaceutical Sciences and Research,  2016; 7(10): pp 4074-4084 / eISSN:  0975-8232 pISSN: 2320-5148
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A new phenanthraquinone from the stems of Bauhinia variegata L. /  Y Y Zhaim C B Cuim B Cai, B Han,  Q S Sun / Journal of Asian Natural Products Research,  2005; 7(6) /
DOI: https://doi.org/10.1080/10286020410001721140

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