Family Arecaceae
Paminta
Piper nigrum Linn.
BLACK PEPPER
Hu-chia

Scientific name  Other names 
Piper glabrispicum  C. DC. Malisa (Tag.) 
Piper nigrum Linn. Paminta (Tag.) 
  Pamienta (Span.) 
  Pepper (Engl.) 
  Hu-chia (Chin.)

Gen info
There is an estimated total of 1200 species of Piper in the pantropical and neotropical regions. Works on Philippine wild Piperaceae have been extensive. Candole (1910) reported 133 species of Piper and 26 of Peperomia; Merill (1923), 115 Piper, 25 Peperomia, and Quisumbing (1930), documented 87 Piper and 21 Peperomia.

Botany
Paminta is a stout climber with smooth branches, 2 to 3.5 mm in diameter. Leaves are somewhat leathery, broadly ovate to oblong-elliptic, 10 to 13 cm long, 3.5 to 8 cm wide, with pointed, rounded, or heart-shaped based, 7-plinerved, smooth on both surfaces. Rachis is hairy. Bracts of the female cupular receptacles are short, whole, adnate, without raised margins. Flowers are usually dioceous (having the male and female organs). Female spikes are pendulous, 6.5 to 10.5 cm long. Fruits are crowded, sessile, rounded, about 4 mm long, 3 mm in diameter, with 3 or 4 stigmas.

Distribution
Limited cultivation in the Philippines.
Also cultivated in all tropical countries of the Old World, and also in Brazil and in the West Indies.

Constituents
- Black pepper has been found to contain piperine, alkamides, piptigrine, wisanine, dipiperamide D, and dipiperamide E.
- The pepper contains an active resin (oleoresin, responsible for the known pungent taste and aromatic odor), a volatile oil, starch, gum, a small quantity of fatty oil in the mesocarp, and about 5% of inorganic matter, besides the alkaloid, peperine, and a volatile alkaloid probably identical with pepperidine.
- Contains an alkaloid piperine, 5 - 9%; piperidine, 5%; mesocarp contains chavicine.
- Piperine the active principle, has the same chemical composition as morphine, although it is almost devoid of taste, color or smell, and is resolvable into piperic acid and a colorless liquid alkaloid, piperidine.


Properties
Considered acrid, astringent, rubifacient, stimulant, counterirritant, stomachic, carminative.
Roots considered tonic, stimulant, cordial and anthelmintic.

Parts utilized
Roots, leaves, seeds.

Uses
Edibility / Culinary
• The dried fruits furnish the black pepper of commerce. When the outer shell is removed, the product is white pepper.
• The use of pepper as spice and condiment dates back to early times.
• Used for large-scale preservation of food, sausage making, etc.
Folkloric
In the Philippines, used as stimulant and rubefacient. Piperine also used as antiperiodic.
Decoction used as mouthwash for toothache; rubifacient in alopeicia and skin diseases.
Liniment used in chronic rheumatism.
Used in dyspepsia, flatulence, gonorrhea, cough, hemorrhoids and intermittent fevers.
Decoction used for obstinate intermittent fever and flatulent dyspepsia.
Used a febrifuge, with brandy and anise, in various forms of malarial fevers.
Externally pepper is rubefacient and used as counterirritant.
In decoction, used as mouthwash for toothache.
Used as rubefacient in alopecia and skin diseases.
Infusion used as gargle for afflictions of the throat.
Juice of leaves boiled in oil and applied externally for scabies.
Ointment mixed with lard used against Tinea capitis.
Used in shellfish and mushroom poisoning.
Mixed with honey and ginger, used by Malay as abortifacient.
Roots used as antihelmintic.
Toasted berries used for stopping vomiting associated with cholera.
Used for vertigo, paralytic and arthritic disorders.
Black pepper is corrective for fish, flesh, shell-fish and mushroom poisoning.
Malay women use black pepper as an abortifacient, taken in pills with honey and ginger.
In Iraian traditional medicine, used to relieve menorrhagia in women.
In Ayurveda, paste of black pepper is used for boils, piles, rheumatic pains, headache, prolapsed rectum, toothaches. Pepper is given for dyspepsia, flatulence, diarrhea, cholea, cough, gonorrhea and malarial fever.


Studies
Spasmolytic / Anti-menorrhagia:
(1) There was spasmolytic effect of the black pepper extract probably through involved voltage dependent calcium channels and B-adrenoreceptors. (2) Spasmolytic Activity of Piper Nigrum Fruit Aqueous Extract on Rat Non-Pregnant Uterus: The results support the traditional use of black pepper for relief of menorrhagia.
Anticholinesterase Inhibitory Activity:
In vitro study of extracxxt of P. nigrum seeds showed 50-65% inhibitory activity on acetylcholinesterase.

Antispasmodic:
Antispasmodic Effect of P Nigrum Fruit Hot Water Extract on Rat Ileum: Study showed spasmolytic effect on rat ileum probably mediated via Ca+ influx. 
Analgesic:
Analgesic Activity Of Piper Nigrum Extract Per Se And Its Interaction With Diclofenac Sodium And Pentazocine In Albino Mice: Piper nigrum alone did not show any significant analgesic activity. However PN extract significantly increased the analgesic activity of diclofenac sodium and pentazocine.
Pharmacognostical Studies: Root distillation yielded 0.39% essential oi, with a total yield of 0.79% piperine from the root.
Neural Effects: In vitro study using whole-cell patch-clamp electrophysiology, piperine, a pungent alkaloid, showed a similar agonist effect on human vanilloid receptonr TRPV1 as capsaicin. Piperine, however, could induce greater receptor desensitization and exhibit greater efficacy than capsaicin.
Antibacterial: (1) Study yielded an isobutyleicosatrienamide, pellitorine, trachone, pergumidiene and isopiperolein B. All the isolated compounds were active against B subtilis, B spaericus, K aerogenes and Chromobacterium violaceum. (2) Study results showed excellent inhibition of the growth of Gram positive bacteria ( Staph aureus, followed by Bacillus cereus and Strep faecalis) and Gram negative bacteria (Pseudomonas aeruginosa followed by Salmonella typhi and E coli.)
Larvicidal : Study demonstrated the potential of P nigrum extracts against larvae of Cx quinquefasciatus and its benefits for the development of new cost-effective and environmentally friendly larvicide for mosquito control.
Antiepileptic : Study demonstrated anticonvulsant activity of the water extract of P nigrum attributed to an antagonistic action at NMDA (N-methyl-D-aspartate) receptors.
Antioxidant : Study showed both water extract and ethanol extract exhibited strong total antioxidant activity.
Anti-Inflammatory: Study in Wistar albino rats of a polyhedral formulation containing extracts from seven medicinal plants including P. nigrum showed 31.3% inhibition against carrageenan-induced acute inflammation.
Diabetes Protective Effects: Study in Alloxan-induced diabetic rats showed oxidative stress playing a key role in diabetes, and treatment with P. nigrum and V. rosea are useful in controlling not only glucose and lipid levels but may also help in strengthening the antioxidant potential.
Anti-Hepatotoxic / Antioxidant: Study showed an ethanol extract of P. nigrum root is an efficient hepatoprotective and antioxidant agent against CCl4-induced liver injury. The hepatoprotective effect was supported by histopathological observations.
Hepatoprotective: Study showed the ethanol extract of P. nigrum significantly reduced the HP, serum enzymes and TBL and inhibited fibrosis induced by thioacetamide.

Availability
Wild-crafted. 

Last Update May 2011

Photo © Godofredo Stuart / StuartXchange
OTHER IMAGE SOURCE: Piper nigrum / File:Koeh-107.jpg / Franz Eugen Köhler / Köhler's Medizinal-Pflanzen / 1897 / Public Domain / Wikimedia

Additional Sources and Suggested Readings
(1)
Spasmolytic Activity of Piper Nigrum Fruit Aqueous Extract on Rat Non-Pregnant Uterus / Iranian Journal of Pharmacology and Therapeutics / 6:35-40, 2007
(2)
Antispasmodic Effect of P Nigrum Fruit Hot Water Extract on Rat Ileum / Pakistan Journal of Biological Sciences / 2008
(3)
CRC Handbook of Ayurvedic Medicinal Plants / L D Kapoor
(4)
Analgesic Activity Of Piper Nigrum Extract Per Se And Its Interaction With Diclofenac Sodium And Pentazocine In Albino Mice / S Pooja et al / Internet Journal of Pharmacology / ISSN: 1531-2976
(5)
PHARMACOGNOSTICAL STUDIES ON THE ROOTS OF PIPER NIGRUM L. III: DETERMINATION OF ESSENTIAL OIL AND PIPERIN / S Hu et al / ISHS Acta Horticulturae 426: International Symposium on Medicinal and Aromatic Plants
(6)
Antibacterial constituents from the berries of Piper nigrum / S.Venkat Reddy et al / Phytomedicine, Volume 11, Issue 7, Pages 697-700
(7)
Larvicidal effects of crude extracts of dried ripened fruits of Piper nigrum against Culex quinquefasciatus larval instars / K Vasudevan et al / J VECTOR BORNE DIS 46, JUNE 2009
(8)
Effects of Piper nigrum L. on epileptiform activity in cortical wedges prepared from DBA/2 mice / Ruo Qi Hu and J A Davies / Phytotherapy Research • Volume 11 Issue 3, Pages 222 - 225
(9)
The antioxidant and radical scavenging activities of black pepper (Piper nigrum) seeds / Ilhami Gulcin / Summary International Journal of Food Sciences and Nutrition • 2005, Vol. 56, No. 7, Pages 491-499 / DOI 10.1080/09637480500450248

(10)
Black pepper (Piper nigrum) / Sigma-aldrich
(11)
PROTECTIVE EFFECTS OF PIPER NIGRUM AND VINCA ROSEA IN ALLOXAN INDUCED DIABETIC RATS / M. KALEEM, SHEEMA, H. SARMAD AND B. BANO / Indian J Physiol Pharmacol 2005; 49 (1) : 65–71
(12)
Anti-hepatotoxic and anti-oxidant effects of extracts from Piper nigrum L. root / Xinpeng Bai, Weimin Zhang et al / African Journal of Biotechnology Vol. 10 (2), pp. 267-272, 10 January, 2011
(13)
Antibacterial activity of black pepper (Piper nigrum Linn) with special reference to its mode of action on bacteria / Pavithra Vani Karsha and O Bhagya Lakshimi / Indian Journ of Natural Products and Resources, Vol 1(2), June 10, 2010, pp 213-215


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