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Family Myrsinaceae

Coral berry
Ardisia crenata Sims
HEN'S EYES

Scientific names Common names
Ardisia crenata Sims Abre a noel (French)
Ardisia crenulata Lodd. Christmas berry (Engl.)
  Coral berry (Engl.)
  Coral bush (Engl.)
  Hen's eyes (Engl.)
  Scratch throat (Engl.)
  Spice berry (Engl.)


Botany
The plant is an evergreen glabrous shrub with many branches, growing to a height of 1.5 meters. Leaves are alternate, simple, dark green, leathery, elliptic lanceolate or oblanceolate with crenate or undulate margins. Flowers are small, white or pink. Fruit is a drupe, coral red and single-seeded.

Distribution
Cultivated in gardens for its decorative red fruits.
A popular pot plant.

Parts utilized
Roots

Uses
Folkloric
• No folkloric medicinal use in the Philippines.
• Elsewhere, root isconsidered anodyne, depurative, febrifuge; used to stimulate blood circulation.
Others
• Provides a dense canopy.

Studies
Triterpenoid Saponins / Ardisiacrenoside / Cytotoxicity: (1) Study isolated two novel triterpenoid saponins – ardisicrenoside A and adrisicrenoside B – and two known triterpenoid saponins, ardisicrispins A and B. (2) Ardisiacrenoside, a new triterpenoid pentasaccharide was isolated from A crenata with five closely related triterpenoid saponins. Their cytotoxic activities were evaluated againszt human tumor cell lines.
Potential Source of Therapeutic Agents: There are more than 500 species of Ardisia throughout the tropical and subtropical regions, several used as ornamentals, food and medicines. Species of Ardisia are rich in novel and biologically potent phytochemical compounds such as bergenin and ardisin. The report presents the potential of the genus as a source of therapeutic agents.
Bergenin / Pharmacologic Activities: (1) Study isolated a new bergenin derivative from the root of A crenata – 11-o-syringylbergenin. Other compounds identified were spinasterol, fatty acids, beta-sitosterol-beta-D-glucoside, norgergenin and sucrose. (2) Studies have shown bergenin to possess a wide range of biological activities: antiulcer, hepatoprotective, antiviral, antidiabetic, anti-inflammatory, among others.
Ardisiacrispin A and B / Pro-Apoptotic / Anticancer: Study investigating the anticancer activity of ardisiacrispin A+B on several human cancer lines showed it could inhibit the proliferation of Bel-7402 cells by inducing apoptosis and dissembling microtubule.
Anti-Thrombin Activity: In a study of 30 plants from central Florida for its antithrombin activity, Ardisia crenata was one of seven that demonstrated activity of 80% or higher in a chromogenic bioassay system.

Availability
Wild-crafted.


Additional Sources and Suggested Readings
(1)
Triterpenoid saponins from Ardisia crenata / Zhonghua Jia et al / Phytochemistry • Volume 37, Issue 5, November 1994, Pages 1389-1396 / doi:10.1016/S0031-9422(00)90418-7
(2)
The genus Ardisia: a novel source of health-promoting compounds and phytopharmaceuticals / Hideka Kobayashi and Elvira de Mejia / Journal of Ethnopharmacology . Volume 96, Issue 3, 15 January 2005, Pages 347-354/ doi:10.1016/j.jep.2004.09.037
(3)
Studies on the chemical constituents of Ardisia crenata Sims / Zhongguo Zhong Yao Za Zhi / Dec 1989 /
(4)
Pro-apoptotic and microtubule-disassembly effects of ardisiacrispin (A+B), triterpenoid saponins from Ardisia crenata on human hepatoma Bel-7402 cells / Min Li et al / Journal of Asian Natural Products Research, Volume 10, Issue 8 August 2008 , pages 729 - 736 / DOI: 10.1080/10286020802016198
(5)
Ardisia crenata - Sims. / Coralberry / Plants For A Future
(6)
Antithrombin activity of medicinal plants from central Florida / Natalya Chistokhodova et al / Journal of Ethnopharmacology . Vol 81, Issue 2, July 2002, Pages 277-280/ doi:10.1016/S0378-8741(02)00097-1
(7)
Cytotoxic triterpenoid saponins from the roots of Ardisia crenata / Zhong-Fei Zheng et al / Journal of Asian Natural Products Research, Volume 10, Issue 9 September 2008 , pages 833 - 839 / DOI: 10.1080/10286020802102568


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