HOME      •      SEARCH      •      EMAIL    •     ABOUT


Family Caprifoliaceae

Honeysuckle
Lonicera japonica Thunb.
JAPANESE HONEYSUCKLE

Jin yin hua

Scientific names Common names
Lonicera japonica Thunb. Honeysuckle (Engl.)
Nintooa japonica (Thunb.) Sweet. Halls honeysuckle (Engl.)
Ren dong (Chin.) Japanese honeysuckle (Engl.)
  Madre silve (Span.)
  Jin yin hua (Chin.)
  Woodbine (Engl.)

Other vernacular names
CHINESE: Jin yin teng
FRENCH: Chèvrefeuille du Japon
JAPANESE : Suikazura, Suikazura, Suikazura, Suikazura.
KOREAN : In dong deong gul.
RUSSIAN : Zhimolost' iaponskaia.

Botany
This ornamental plant, Japanese honeysuckle, is a hardy, low-climbing or trailing shrub, up to 5 meters or more in length. Leaves are oblong, oblong-ovate, or ovate, 3 to 6 centimeters long, 1.5 to 2.5 centimeters wide, pointed or blunt at the tip, blunt at the base and borne on short petioles. Flowers are tubular, 3 to 4 centimeters long, white, but turning yellow with age, borne in pairs in axils of the leaves on young shoots. Corolla is smooth, the tube slender and widening gradually, the limb has two lips, the upper lip broad, erect and divided into four-strap segments, and the lower lip having one linear-strap-shaped recurved segment. The berries are black.

Distribution
- Ornamentally cultivated for its fragrant, attractive and profuse flowers.
- A recent introduction.
- Native of Japan.

Parts utilized
Vine, leaves and flowers.

Constituents
• Vine contains saponin, tannin and ash.
• Vine, leaves and flowers considered antifebrile, corrective and astringent.
Volatile oils in the flower and stems were highly similar to each other – palmitic acid and linoleic acid are the highest principles.
Study yielded seven compounds: luteolin, luteoloside, quercetin, quercetin-3-0-beta-D-glucoside, quercetin-7-0-beta-D-glucoside, rutin, chlorogenic acid.

Properties
• Considered antibacterial, antiinflammatory, antispasmodic, antiviral, depurative, diuretic, febrifuge.

Uses
Edibility
Flowers and leaves.
• Tea made from leaves, buds and flowers.
• Leaves cooked as vegetable. (See toxicity concerns below)

Folkloric
• In Chinese medicine, vine, flowers and leaves are used to increase vitality and lengthen life.
• Used for infections and poisoning.
• Considered antisyphilitic.
• Infusion of stems and flowers used for common colds, upper respiratory infections and flu-like symptoms.
• Infusion used in lotions for ulcers and abscesses.
• Flowers applied as wash for skin inflammations, rashes and sores.
• In Brazil, used as depurative and to facilitate childbirth.

Studies
Biflavonoids / Anticancer: Biflavonoids isolated from Lonicera japonica and Benincasa hispida displayed different patterns of growth inhibition among the human cancer cell lines.
Acute and Subacute Toxicity Studies: The ethanol extract of leaves of Lonicera japonica showed no toxicity on hematologic, blood chemistry and gross and histopathologic parameters.
Luteolin / Anti-Inflammatory: Luteolin, isolated from the flowers of Lonicera japonica, inhibited the induction of inflammatory cytokines, exerting a regulatory effect on mass cell-mediated inflammatory diseases, such as IBD, RA and allergy diseases.
Antipyretic: Study showed L japonica to have obvious antipyretic effects on IL-1ß-induced febrile rabbits and acts by inhibiting expression of EP3 mRNA in the POAH.
Anti-Angiogenic / Antinociceptive / Anti-Inflammatory: Study on the ethanolic extract of L japonica showed antiangiogenic, antinociceptive and antiinflammatory activities.
Growth Hormone Release: Study showed induction of rat growth hormone (rGH) by addition of methanol extract in rat pituitary cell culture.
Apoptosis: Study results suggested the photoactivated Lj extract-induced apoptosis is mediated by change in distribution of cytoskeleton. Results indicate the cytoskeleton is the potential target in the photoactivated Lonicera japonica extract-induced CH27 cell apoptosis.

Toxicity
• Leaves contain saponins; although toxic, are poorly absorbed and cooking, changing the water once, remove most of the saponins.

Availability
Wild-crafted.

Last Update September 2012

IMAGE SOURCE: Public Domain / File:Lonicera japonica flowers.jpg / Author: SS_Johnny / Cropped / Wikimedia Commons

Additional Sources and Suggested Readings
(1)
Lonicera japonica - Thunb. / Japanese Honeysuckle / Plants For A Future
(2)
Anticancer activity of biflavonoids from Lonicera japonica and Benincasa hispida on human cancer cell lines / D. Pradhan et al. / Journal of Pharmacy Research 2009, 2(5),983-985
(3)
Acute and subacute toxicity study of the ethanol extract from Lonicera japonica Thunb / Thanabhorn S et al / Journal of ethnopharmacology, 2006, vol. 107, no3, pp. 370-373
(4)
Luteolin Isolated from the Flowers of Lonicera japonicaSuppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells / Ok-Hwa Kang et al / Molecules 2010, 15, 385-398; doi:10.3390/molecules15010385
(5)
Lonicera japonica-induced inhibition of interleukin-1 beta thermogenesis and E-type prostaglandin receptor-3 expression in the preoptic area of rabbits / Jun Dong et al / NEURAL REGENERATION RESEARCH / 2008 3(2)
(6)
Anti-angiogenic, antinociceptive and anti-inflammatory activities of Lonicera japonica extract / Yoo Hye-Jung et al / Journal of pharmacy and pharmacology, 2008, vol. 60, no6, pp. 779-786
(7)
Induction of Growth Hormone Releace by the Extracts of Lonicera japonica THUNB. / Jung D Y et al / Korean-Journal-of-Pharmacognasy. (2003. 9). V. 34(3) P. 256-262.
(8)
Lonicera japonica / Catalogue of Life, China
(9)
Sorting Lonicera names / Maintained by: Michel H. Porcher, / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE
(10)
Studies on chemical constituents of the extract of Lonicera japonica / Chen QZ, Lin RC, Wang GL, Li FM. / Zhong Yao Cai. 2010 Jun;33(6):920-2.
(11)
Rottlerin Inhibits Lonicera japonica-Induced Photokilling in Human Lung Cancer Cells through Cytoskeleton-Related Signaling Cascade / Bang-Jau You, Yang-Chang Wu, Bo-Ying Bao, Chi-Yu Wu, Ya-Win Yang, Yu-Hao Chang, and Hong-Zin Lee / Evidence-Based Complementary and Alternative Medicine, Vol 2011 (2011) / doi:10.1155/2011/193842


HOME      •      SEARCH      •      EMAIL