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Family Dioscoreaceae
Ubi-ubihan
Dioscorea bulbifera Linn.
AIR POTATO

Huang du

Scientific names Common names
Dioscorea bulbifera Linn. Aribukbuk (Ilk.)
Dioscorea heterophylla Roxb. Bayag-kabayo (Tag.)
Dioscorea latifolia Benth. Dadakan (Bag.)
Dioscorea oppositifolia Campbell Pulugan (Bik.)
Dioscorea sativa Hort. Ubi-ubihan (Tag.)
Dioscorea violacea Baudon Utong-utoñgan (Tag.)
Dioscorrea tamifolia Salisb. Huang du (Chin.)
Helmia bulbifera (L.) Kunth. Air potato (Engl.)
  Bitter yam (Engl.)
  Potato yam (Engl.)

Botany
Ubi-ubihan is a climbing or twining, dioecious, smooth, unarmed vine reaching a length of several meters. Tubers are rounded, not larger than a man's fist. Stems are teret, bearing numerous little tubers. Leaves are simple, ovate, 7 to 14 cm long, with a broad and prominently heart-shaped base, a broad and rounded sinus, rounded lobes, and 7- to 9-nerved. Spikes are slender, panicled, numerous, 8 to 10 cm long, and rather densely many-flowered. Flowers are about 3 mm long. Capsules are longer than broad. Seeds are winged at the base only.

Distribution
In thickets at low and medium altitudes.
Sometimes cultivated as an oddity for its tubers.
Also occurs in India to China and Malaya.

Constituents
- Tubers reported to contain a poisonous glucoside.
- Study yielded14 compounds: : stigmasterol, mono-arachidin, 1,7-bis-(4-hydroxyphenyl)-1E,4E,6E-heptatrien-3-one, behenic acid, demethyl batatasin IV, 2,3'-di-hydroxy-4',5'-dimethoxybibenzyl, diosbulbin B, diosbulbin D, docosyl ferulate, 7-bis-(4-hydroxyphenyl) -4E, 6E-heptadien-3-one, 5,3,4-trihydroxy-3,7-dimethoxyflavone, tristin, protocatechuic acid, adenosine.
- Study yielded three norclerodane diterpenoids: diosbulbins K-M, and one enoglycoside, diosbulbinoside G, with four norclerodane diterpenoids, disobulbins B, E, F and G from the rhizomes.

Properties
- In the wild, tubers, when fresh, are bitter.
- Cultivated tubers are less or non-bitter.
- Tubers considered tonic, expectorant, aphrodisiac and anthelmintic.

Parts used
Tubers.

Uses

Culinary
Tubers are reported edible, with a flavor similar to potato.
Some report the tubers are poisonous when raw.
Folkloric
Tubers taken internally as remedy for dysentery and syphilis.
Tubers used as resolvent for boils and as diuretic.
Powdered tubers used as application for sores, piles and to stop diarrhea.
In India, a folk remedy used to cure wounds, leucoderma and boils. Also, used as tonic, expectorant in asthma, as aphrodisiac and anthelmintic.
In Chinese medicine, used to treat diseases of the lungs, kidney, spleen and many types of diarrhea.


Studies
Anticancer:
Anticancer screen carried out in vivo with HepA in mice showed active anticancer compounds from the hydrophobic constituents of D. bulbifera. The anticancer effects were related to direct toxicity on tumor cells.
Liver Toxicity Studies: Study to evaluate the liver-toxic fraction in Rhigoma of Disocorea bulbifera is rats showed significant liver toxicity. The chloroform extract was the liver toxic fraction.
Antioxidant: Study showed impressive levels of enzymatic (GPx, CAT, SOD, G6PD, GST) and commendable stores of non-enzymatic antioxidants (reduced GSH, vitamins C and E).
Antitumor Promoting / Constituents: Study of rhizome extracts yielded 28 compounds. some showed different inhibitory activities against tumor promotion of JB6 (CI22 and CI41) cells. The EtOAc and n-BuOH fractions were found to be potent anti-tumor promoters.
Hepatotoxicity: Study in mice showed the EtOAc fraction contains the main toxic ingredients of D. bulbifera rhizome, and the mechanism of hepatotoxicity may be due to liver oxidative stress injury in mice.
Wound Healing: Study of tuber extract revealed significant wound healing activity, high rate of wound contraction and decrease in the period for epitheliazation.
Antihyperglycemic / Antidyslipidemic: Study of aqueous extract of tubers in glucose-primed and STZ-treated Wistar rats showed significant antihyperglycemic and antidyslipidemic effects.
Myocardial Protective Effect: Study of hydroalcoholic extract showed D. bulbifera could ameliorate myocardial ischemia and reperfusion injury by improving ventricular function and inhibition of cardiomyocyte necrosis and apoptosis.
Anthelmintic: Study of D. bulbifera extract showed significant anthelmintic activity, especially against Eicinia fetida, Ascardia galli and Raillietina spiralis. Results provide a rationale for its traditional use as an anthelmintic.
Analgesic / Anti-Inflammatory: Study of aqueous and methanol extracts from the dry bulbils of D. bulbifera L. var sativa showed a dose-dependent inhibition of pain and inflammation. The exhibited potent analgesic and anti-inflammatory effects may result from inhibition of imflammatory mediators such as histamine, serotonin and prostaglandins.

Availability
Wild-crafted.

Last Update November 2011

IMAGE SOURCE :Dioscorea bulbifera / Forest and Kim Starr / Plants of Hawaii / Creative Commons Attribution 3.0 License / alterVISTA
IMAGE SOURCE: Leaf Closeup / Dioscorea bulbifera / Leaves at Tree Top Park, Florida / Forest and Kim Starr - Plants of Hawaii / Creative Commons Attribution / alterVISTA

Additional Sources and Suggested Readings
(1)
Sorting Dioscorea names / Multilingual Multiscript Plant Name Database
(2)
Anticancer effects of various fractions extracted from Dioscorea bulbifera on mice bearing HepA / Zhongguo Zhong Yao Za Zhi, 2004 Jun;29(6):563-7.
(3)
Studies on liver-toxicity in rhigoma of Dioscorea bulbifera
/ Xing-Qi Tan, Jin-Lan Ruan et al / Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica (2003), Vol 28, Issue: 7, Pages: 661-663 / PubMed ID: 15139116/
(3)
Screening of antioxidant potentials in Dioscorea bulbifera / M Suriyavathana and S Indupriya / Int. J. of Pharm. & Life Sci. (IJPLS), Vol. 2, Issue 4: April: 2011, 661-664
(4)
Constituents from anti-tumor-promoting active part of Dioscorea bulbifera L. in JB6 mouse epidermal cells / Hyiyuan Gao, Bailling Hou et al / Asian Journal of Traditional Medicines, 2007, 2 ( 3 )
(5)
Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. / Wang J, Ji L, Liu H, Wang Z / Biosci Trends. 2010 Apr;4(2):79-85.
(6)
Wound Healing Activity of Dioscorea bulbifera Linn / Panduraju.T,Veera Raghavulu Bitra et al / Journal of Pharmacy Research, Vol 3, No 12 (2010)
(8)
ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC ACTIVITY OF AQUEOUS EXTRACT OF DIOSCOREA BULBIFERA TUBERS
/ Zabeer Ahmed, Mohd Zahoor Chishti, Rakesh Kamal Johri et al / Diabetologia Croatica 38-3, 2009
(9)
Chemical constituents from tubers of Dioscorea bulbifera / Gang Wang, Binbin Lin, Jinsong Li et al / Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica (2009)
Vol 34, Issue: 13, Pages: 1679-1682 / PubMed ID: 19873780
(10)
Norclerodane diterpenoids from rhizomes of Dioscorea bulbifera / Hai Liu, Gui-Xin Chou et al / Phytochemistry, Vol 71, Issue 10, July 2010, Pages 1174-1180 / doi:10.1016/j.phytochem.2010.04.002
(11)
Protective role of air potato (Dioscorea bulbifera) of yam family in myocardial ischemic reperfusion injury / Hannah Rachel Vasanthi, Subhendu Mukherjee et al / Food Funct., 2010, 1, 278–283
(12)
Investigation of anthelmintic potential of some plants claimed by tribals of satpuda hills / Satish B. Kosalge, Ravindra A. Fursule / Int.J. PharmTech Res.2009,1(1)
(13)
Analgesic and Anti-Inflammatory Properties of Extracts from the Bulbils of Dioscorea bulbifera L. var sativa (Dioscoreaceae) in Mice and Rats / M Mbiantcha, A Kamanyi, R B Teponno et al / Evidence-Based Complementary and Alternative Medicine, Vol 2011 (2011) / doi:10.1155/2011/912935


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