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Family Amaranthaceae
Gomphrena globosa L.

Qian ri hong

Scientific names Common names 
Amaranthoides globosa (L.) M.Gomez Bokingon (Tag.) 
Amaranthoides globosus M.Gomez Botbotones (Ilk.) 
Gomphrena eriopoda Gillies ex Moq. Botoncillo (Sp.) 
Gomphrena globosa L. Botones-botonesan (Tag.) 
Gomphrena rubra Moq. Bukingan (Tag.)
Gomphrena tumida Seidl ex Opiz Bulah (Bag.) 
Xeraea globosa Kuntze Butingan (S.L.Bis.) 
  Bachelor's button (Engl.)
  Globe amaranth (Engl.)
  Gomphrena (Engl.)
  Thousand day red (Engl.)
Boto-botonesan or phonetic variations are shared by four plants of different species: (1) Mutha (Cyperus rotundus) Boto-botones (2) Gatas-gatas (Euphorbia hirta) botobotonis, botbotonis, botonis (3) Botoncillo (Gomphrena globosa) botbotonis, botones-botonesan, and (4) Botonesan (Hyptis capitata): bababañga, liñga-liñgahan.
Gomphrena globosa L. is an accepted name The Plant List

Other vernacular names
BENGALI: Botam phul, Gulmakhamal, Golkamal.
FRENCH: Immortelle pourpre.
HINDI: Gul-e-makhmal.
MALAYALAM: Vadamalli.
MANIPURI: Chengkruk.

Botoncillo is an erect, branched, pubescent annual, the branches more or less thickened and often purplish at the nodes. Leaves are opposite, petioled, oblong acute or obtuse, 7 to 11 centimeters long. Flowers are numerous, densely crowded in globose heads, the heads are white, pink or purple, solitary, peduncled, 1.5 to 2 centimeters in diameter, subtended by 2 bracts. Bracteoles are 8 to 10 millimeters long, enclosing the flowers, lateral, keeled. Sepals, pubescent, 5, lanceolate, cleft at the tip, usually without staminodes. Ovary 1-celled, 1-ovuled; style short or long, stigmas 2. Fruits are utricles, compressed, and indehiscent.

- In settled areas throughout the Philippines.

- Plant yield flavones and flavonoid glycosides, gomphrenol.
- Flower yields ß-cyanins, gomphrenin I, II, and III.
- Leaves yield methylenedioxyflavonol-gomphrenol.
- Study yielded a triterpenoid saponin (gomphrenoside-1), an new hopane derivative along with known compounds.

- Phytochemical screening yielded saponins, alkaloids, reducing sugars and coumarins. (7)
- Phytochemical evaluation of aerial parts yielded one new triterpenoid saponin (gomphrenoside) and one new hopane derivative (hopan-7ß-ol) along with known compounds, ß-sitosterol-ß-D-glucoside and 1-triacontanol. (11)

- Sweet tasting, antitussive, antiasthmatic.

- Studies have suggested antioxidant, hypoglycemic, anticancer, cytotoxic properties.

Parts utilized
· Flowers.
· Collect the head inflorescence during May to October, during the flowering season.
· Sun-dry.

- Flowers mixed with various kinds of tea or steeped alone.
- Knob petals can be eaten as vegetable.
- Decoction of dried material or 10 inflorescences used for bronchial asthma, acute and chronic bronchitis, whooping cough.
- Decoction of fresh plant used to wash sores.
- Flower decoction used for inflammation of the eyes, difficulty urinating, headaches, and dysentery.
- In Trinidad and Tobago, used for diabetes and for high blood pressure, jaundice, oliguria and other kidney problems and as heart tonic. (3)
- In Myanmar, decoction of plant used for cough.
- In the Guianas, whole plant infusion of the white-flowered variant used as diabetes remedy. Warm infusion of leaf used as sudorific.

Betacyanins: Rapid Identification of Betacyanins from Amaranthus tricolor, Gomphrena globosa, and Hylocereus polyrhizus: Natural betacyanins are studied for its potential as food colorants and antioxidants. Fourteen free and acetylated betacyanins were identified. (1)
Antihypertensive / Low Cytotoxicity: Study of ethanol extract of leaves showed low cytotoxicity in the brine shrimp bioassay and no antimicrobial activity. It promoted a hypotensive effect by significant reduction in arterial blood pressure without change in heart rate. (7)
Antioxidant / Cytotoxicity: Crude methanol extract of G. globosa showed significant free radical scavenging activity. Its hexane soluble fraction showed highest activity. On brine shrimp lethality assay, the chloroform soluble fraction of the crude methanol extract showed highest lethality. (8)
Hypoglycemic / Cytotoxicity: In a study of various fractions, an n-hexane soluble fraction showed significant lowering of blood glucose level in a mice model. Glibenclammide was used as standard drug. (9)
Antioxidant / Flowers: In a study of various extracts of flowers, a methanol extract showed a high content of phenols and flavonoids. It showed potent free radical scavenging activity in the H2O2 and DPPH assays. (10)
Anticancer / Ehrlich Ascites Carcinoma / Aerial Parts: Study investigated the anticancer activity of chloroform extract of aerial parts of GG against Ehrlich Ascites Carcinoma (EAC) induced solid tumor. Results showed a significant anti-cancer activity restoring hematological and biochemical parameters toward normal, with histological evidence of significant reduction of tumor volume. Acute toxicity study showed the extract was non-toxic up to 2000 mg/kbw. (13)
Antidiarrheal: Study evaluated a methanolic extract for anti-diarrheal activity in a castor oil-induced diarrhea model in mice. Results showed statistically significnt anti-diarrheal activity at a dose of 400 mg/kbw. Loperamide was the standard anti-diarrheal drug. (14)

- Wild-crafted. 
- Supplements and tea in the cybermarket.

Godofredo U. Stuart Jr., M.D.

Last Updated April 2016

Photos © Godofredo Stuart / StuartXchange

Additional Sources and Suggested Readings
Rapid Identification of Betacyanins from Amaranthus tricolor, Gomphrena globosa, and Hylocereus polyrhizus
/ Yi-Zhong Cai, Jie Xing, Mei Sun, and Harold Corke
Phytochemical investigation of Gomphrena globosa aerial parts / Indian journal of chemistry/ 2004, vol. 43, no10, pp. 2223-2227
Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus / Cheryl A Lans / J Ethnobiol Ethnomed. 2006; 2: 45. / doi: 10.1186/1746-4269-2-45.

Gomphrena globosa L. is an accepted name / The Plant List
Gomphrena / Common names / Flowers of India
Medicinal Plants of the Guianas (Guyana, Surinam, French Guiana) / Botany.si.edu
Phytochemical screening and evaluation of cytotoxic, antimicrobial and cardiovascular effects of Gomphrena globosa L.(Amaranthaceae) / Daniel Dias Arcanjo et al / Journal of medicinal plant research (Impact Factor: 0.59). 04/2011; 5(10):2006-2010.
Antimicrobial, Antioxidant and Cytotoxic Activities of Gomphrena globosa (L.) / Md. Hamiduzzaman and A.T.M. Zafrul Azam / Bangladesh Pharmaceutical Journal 15(2): 183-185, 2012
Significant Hypoglycemic Activity from Gomphrena globosa (Amaranthaceae) in Mice Model / Hamiduzzaman Md. / Universal Journal of Pharmacy, 2013, 2(5): pp 68-72
Phytochemical investigation of Gomphrena globosa aerial parts
/ Biswanath Dinda, Biplab Ghosh, Shiho Arima, Nariko Sato, & Yoshihiro Harigaya / Indian Journal of Chemistry, Vol 43B, Oct 2004, pp 2223-2227
Gomphrena globosa / Synonyms / The Plant List
Anticancer screening of Gomphrena globosa against ehrlich ascites carcinoma in swiss albino mice
/ S. T. Latha *, N. N. Rajendran , G. Babu / Journal of Chemical and Pharmaceutical Research, 2013, 5(2):283-289
Evaluation of Anti-diarrheal Activity of Gomphrena globosa (L) in Animal Mode
l / Md. Hamiduzzaman* / ASA University Review, Vol. 8 No. 1, January–June, 2014

It is not uncommon for links on studies/sources to change. Copying and pasting the information on the search window or using the DOI (if available) will often redirect to the new link page.

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